
Phion technology

pH Responsive
Cationic
Helical
Conditional Cell Penetration
RALA is a 30 amino acid peptide with the following advantages for precision drug delivery:
Secondary
Amphipathic
RALA nanoparticles have many advantages

High cell transfection / cellular entry without associated toxicity

Self-assembly with nucleic cargo, irrespective of size

Stable nanoparticle with no need for cold chain storage

Non-immunogenic nanoparticles facilitate repeated dosing

Protection of drug cargo while increasing circulatory half-life

Demonstrated formulation lyophilisation and easy scale up
RALA : HOW DOES IT WORK?
RALA is optimised for both localised and systemic delivery, excelling in in vitro, in vivo and ex vivo applications.

PUBLICATIONS
Over 20+ studies have been published using the RALA system, ranging from the fundamental design and application of an efficient cell penetrating peptide to use as a potential therapeutic mRNA vaccine candidate.
Below is a selection of publications of special note: